Due to the controversial nature of this topic and the target audience (young people) it is important that the reader reads the complete answer and not
simply one paragraph or a few sentences. Taking one part of the answer out of context can lead to a misinterpretation of the intended message.
Paul Dillon speaks to thousands of students across Australia providing information on alcohol and drugs, particularly in relation to looking after
themselves and their friends. Some young people make contact with him to ask questions that they did not feel comfortable asking in front of their peers.
The Real Deal on Drugs allows young people to ask questions about drugs and provides them with access to accurate and up-to-date information.

I recently took ecstasy but felt no effects whatsoever. Is this normal or is this a dangerous sign of some kind? Could it have affected me without me being aware of it? I also take 150mg of Zoloft everyday for depression, could this have something to do with me not having any effect.

There are really two issues that need to be covered here - firstly, why would someone who has taken ecstasy not get the effect they were expecting, and secondly, a discussion on using drugs like ecstasy if you are on medications, particularly those used to treat mental health conditions.

There are a number of things to remember when taking an illegal drug that could result in someone not experiencing the desired effect:
  • There may not have been any active substance in your pill or capsule. Analysis of pills, capsules and powders sold as ecstasy shows that some contain no active substance at all and may in fact contain household products like Epsom salts and bicarbonate of soda! Sometimes they just contain caffeine. As much as we warn about poisonous substances being in ecstasy (and that may certainly be the case), sometimes there's nothing in them!

  • If others with you took a pill from the same batch and they got an effect remember that different people will be affected differently by exactly the same drug. Just because someone had a very strong effect after taking a pill, it doesn't necessarily mean that others will too. This is why one person may die or get extremely sick after taking a pill, while all the others around them who took exactly the same thing had no problems at all – this is called 'individual difference' and is incredibly important to remember in regards to drugs!

  • There are many other things that could impact on the effect the drug has on the user – what you ate beforehand, how much you ate, your mood when you took the drug and who you were with and so many others. Would this account for getting no effect whatsoever? Most probably not but sometimes people's expectations of what a drug experience is going to be like may exceed what actually happens …

Most importantly, you have been diagnosed with depression and are being treated … taking a drug like ecstasy when you're on medication for a mental health issue is simply not a good idea and can possibly make your condition even worse. There is a great little article on mixing ecstasy with Zoloft at the following link: http://goaskalice.columbia.edu/answered-questions/zoloft-and-mdma - take a look at it and think very carefully about ever using the drug again. Although many people regard ecstasy as a 'low-risk' drug, things can still go wrong - your mental health is so important and when you have a pre-existing condition, using a drug like ecstasy that plays around with your brain chemistry could be even more dangerous.